SimThyr 3.3.3

Operating systemsOS : Windows 2000,Windows XP/2003/2008,Windows Vista,Windows 7,MAC OS,Linux,FreeBSD
Program licensingSoftware Licensing : Open source
CreatedCreated : Dec 13, 2011
Size downloadDownload size : 1.2 MBytes
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SimThyr 3.3.3 A Simulation Program For Thyroid Homeos...

Thyroid hormones play an essential role for metabolism, growth and differentiation. Therefore, exact regulation of thyroid hormone levels is vital for most organisms. Although the principles of thyrotropic feedback control have been described decades ago we still have not yet gained comprehensive understanding of its dynamics. Recently, significant progress has been made with mathematical modelling of thyroid homeostasis. However, due to nonlinear interactions, these cybernetic modells cannot simultaneously describe static and dynamic behaviour. This gap may be filled with computer simulation that additionally facilitate an intuitive insight into the dynamics of thyrotropic feedback. SimThyr by J. W. Dietrich is a simulation program for the pituitary thyroid feedback control that is based on a parametrically isomorphic model of the overall system. Applications of this program cover research, including development of hypotheses, and education of students in biology and medicine, nurses and patients. SimThyr 3.3.3 helped do prove a new hypothesis about the emergence of pulsatile TSH release. Furthermore it is used for educational processes at several locations.

What is new in official SimThyr 3.3.3 software version? - Introduction of two-way sensitivity analysis. 3.3.3: Bug fixes for structure parameters editor (SVN commits r289 to r293, 13-IV-2015). 3.3.2: Bug fix release, speed accelerations, GUI improvements for Windows and Mac OS X 10.10 Yosemite. First version to be code-signed for Mac OS X Mavericks and Yosemite (SVN commits r249 to r259, 18-YI-2014). 3.3.1: Bug fixes (SVN commits r238 to r248, 26-VII-2014). 3.3: Two-way sensitivity analysis, new option to switch off circadian TRH rhythm, version handling for scenario files, more flexible handling of units of measurement based on PUMA Repository, bug fixes (SVN commits r182 to r236, 24-V-2014). What is expected in the future? Newly-made SimThyr 3.4 be downloaded from current page, we also looking forward to unconfirmed 3.5 release build. You may download directly, estimated download time by ISDN or CDMA [~128 kbit/s] is 0:01:08. Just write the reviews of the SimThyr. System requirements are unspecified. Program has been scanned and verified by the several antivirus and anti-spyware applications and SimThyr found to be clean. No guide or SimThyr tutorial available. The following languages are supported by SimThyr: English.

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